Computer Aided Drug Design in Taste Masking (CADD)

• Provide an overview of taste masking challenges in drug development and the importance of patient-centric formulation approaches.
• Introduce participants to the principles and techniques of computer-aided drug design and its application in taste masking.
• Share insights into the latest computational tools, methodologies, and software platforms used in taste masking studies.
• Highlight successful case studies and real-world examples where CADD has facilitated the development of palatable medications.
• Foster collaboration and knowledge exchange among participants from academia, industry, and regulatory bodies.
• Identify future research directions and opportunities in the field of taste masking through CADD.

Day 1: Introduction to Computer-Aided Drug Design and Taste Masking
 Basics of Drug Design and Taste Masking

• Introduction to computer-aided drug design (CADD) and its applications in pharmaceutical research 
• Overview of taste masking techniques and their importance in enhancing patient acceptability 
• Challenges and considerations in taste masking of pharmaceutical compounds
  

Principles of Taste Perception and Evaluation

• Understanding the physiology of taste perception 
• Techniques for evaluating taste perception and masking efficacy
• Case studies highlighting successful taste masking strategies 

Computational Techniques in Drug Design 

• Introduction to molecular modeling and simulation methods 
• Structure-based drug design approaches for taste masking
• Virtual screening and ligand-based drug design techniques

Day 2: Computational Tools and Techniques for Taste Masking

Molecular Docking and Binding Analysis 

• Principles of molecular docking and its role in predicting drug-target interactions
• Hands-on session using molecular docking software to identify potential taste masking agents 

In Silico Formulation Design and Optimization 

• Overview of in silico formulation design techniques 
• Predictive modeling for optimizing drug release and taste masking in different dosage forms
• Case studies illustrating successful in silico formulation design approaches

Day 3: Case Studies 

Case Studies on Taste Masking in Various Drug Delivery Systems

• Application of computer-aided drug design in taste masking for oral solid dosage forms, liquids
• Evaluation of taste masking efficacy using computational methods

Interactive Discussion and Future Trends

• Open forum for participants to share their experiences and challenges in taste masking research
• Discussion on emerging trends and future directions in computer-aided taste masking

1. Educational Background: Participants may be required to have a background in pharmaceutical sciences, medicinal chemistry, pharmacology, computational chemistry, or a related field at the undergraduate or graduate level.
2. Research Experience: Some programs may prefer participants with prior research experience in drug design, computational chemistry, pharmaceutical formulation, or taste masking techniques.
3. Computer Skills: Proficiency in computer programming languages (e.g., Python, R), molecular modeling software (e.g., Schrödinger, MOE, AutoDock), and statistical analysis tools may be beneficial for effective participation in the program.
4. Interest and Motivation: Individuals with a strong interest in drug discovery, pharmaceutical formulation, and computational methods, as well as a commitment to advancing their skills and knowledge in these areas, are typically encouraged to apply.
5. Language Proficiency: Depending on the language of instruction and communication, participants may be required to demonstrate proficiency in the relevant language(s), typically English.

• In-depth Understanding of Taste Masking Principles
• Knowledge of Computer-Aided Drug Design (CADD) Techniques
• Familiarity with Innovative Taste Masking Strategies
• Insight into Current Research and Advancements
• Improved Drug Formulation and Patient Adherence